Figure 1From: Plasma cells within granulomatous inflammation display signs pointing to autoreactivity and destruction in granulomatosis with polyangiitisELSs in nasal tissues do not differ between GPA and CRS. (A through D) Immunohistochemistry of GPA displaying CD3+ T lymphocytes (A, brown) surrounding a primary CD20+ B-cell follicle (B, brown color) with a CD21+ FDC network (C, brown), which could be located in proximity to PNAd+ high endothelial venules (D, brown). (E through H) Immunohistochemistry of CRS showing CD3+ T lymphocytes (E, brown) surrounding a primary CD20+ B-cell follicle (F, brown) with a CD21+ FDC network (G, brown) that could be located near PNAd+ high endothelial venules (H, brown). Nuclei are stained in blue with hematoxylin (Figure 1A-H, Figure 2A-G, K, L).Back to article page