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Table 3 Factors associated with low BMD and fracture at multivariate analysis

From: Bone fragility in sarcoidosis and relationships with calcium metabolism disorders: a cross sectional study on 142 patients

  BMD < −-SD Fracture
  OR [95% CI] P OR [95% CI] P
Menopausal female 13.84 [2.28; 84.11] 0.004   
Male ≥50 years 12.2 [1.42; 104.71] 0.023   
Calcium intake <500 mg/d 3.98 [1.19; 13.25] 0.025 3.5 [1.09; 11.27] 0.036
Vitamin D supplements 12.86 [2.98; 55.53] 0.001   
BP treatment 4.6 [1.47; 14.3 ] 0.009   
Fracture 3.88 [0.99 ;15.23] 0.052   
25(OH)D ≤10 ng/ml 1 - 1 -
10 < 25(OH)D ≤20 ng/ml 0.29 [0.08; 1.06] 0.062 2.05 [0.57; 7.45] 0.274
25(OH)D >20 ng/ml 0.96 [0.25; 3.67] 0.95 3.93 [1.02; 15.17] 0.047
Current CS treatment    3.73 [1.06; 13.16] 0.04
Creatinine clearance    0,97 [0.94; 0.99] 0.002
  1. BMD, Bone mineral density; BP, Bisphosphonate; CS, Corticosteroids. Empty cells correspond to variables not included in the multivariate analysis because they were not significant at univariate analysis or to variables included in the multivariate analysis but not retained in the final model because they were no longer significant (for example, age).