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Table 3 Factors associated with low BMD and fracture at multivariate analysis

From: Bone fragility in sarcoidosis and relationships with calcium metabolism disorders: a cross sectional study on 142 patients

 

BMD < −-SD

Fracture

 

OR [95% CI]

P

OR [95% CI]

P

Menopausal female

13.84 [2.28; 84.11]

0.004

  

Male ≥50 years

12.2 [1.42; 104.71]

0.023

  

Calcium intake <500 mg/d

3.98 [1.19; 13.25]

0.025

3.5 [1.09; 11.27]

0.036

Vitamin D supplements

12.86 [2.98; 55.53]

0.001

  

BP treatment

4.6 [1.47; 14.3 ]

0.009

  

Fracture

3.88 [0.99 ;15.23]

0.052

  

25(OH)D ≤10 ng/ml

1

-

1

-

10 < 25(OH)D ≤20 ng/ml

0.29 [0.08; 1.06]

0.062

2.05 [0.57; 7.45]

0.274

25(OH)D >20 ng/ml

0.96 [0.25; 3.67]

0.95

3.93 [1.02; 15.17]

0.047

Current CS treatment

  

3.73 [1.06; 13.16]

0.04

Creatinine clearance

  

0,97 [0.94; 0.99]

0.002

  1. BMD, Bone mineral density; BP, Bisphosphonate; CS, Corticosteroids. Empty cells correspond to variables not included in the multivariate analysis because they were not significant at univariate analysis or to variables included in the multivariate analysis but not retained in the final model because they were no longer significant (for example, age).