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Table 1 Characteristics of individuals without rheumatoid arthritis (RA) or osteoarthritis (OA) at baseline

From: Cardiovascular disease is increased prior to onset of rheumatoid arthritis but not osteoarthritis: the population-based Nord-Trøndelag health study (HUNT)

 

All participants without RA/OA

Later developed RA

Did not develop RA

P-value

Later developed OA

Did not develop OA

P-value

n

33,567

786

32,781

 

3,586

29,981

 

Age 1 (years)

46 (13)

51 (13)

46 (13)

**

52 (10)

45 (13)

**

Sex (female)

18,207 (54.2%)

488 (62.1%)

17719 (54.1%)

**

2,406 (67.1%)

15,801(52.7%)

**

Smoking

   

**

  

**

Current

8,901 (26.5%)

256 (32.6%)

8,645 (26.4%)

 

1,015 (28.3%)

7,886 (26.3%)

 

Former smoker

7,908 (23.6%)

212 (27.0%)

7,696 (23.5%)

 

945 (26.4%)

6,963 (23.2%)

 

Never smoker

15,017 (44.7%)

281 (35.6%)

14,736 (45.0%)

 

1,425 (39.7%)

13,592 (45.3%)

 

Hypertension

12,186 (36.3%)

339 (43.1%)

11,847 (36.1%)

**

1,547 (43.1%)

10,639 (35.5%)

**

Diabetes

454 (1.4%)

19 (2.4%)

435 (1.3%)

*

61 (1.7%)

393 (1.3%)

 

Previous CV disease

1,060 (3.2%)

52 (6.6%)

1,008 (3.1%)

**

158 (4.4%)

902 (3.0%)

**

Angina

673 (2.0%)

35 (4.5%)

638 (1.9%)

**

107 (3.0%)

566 (1.9%)

**

MI

441 (1.3%)

16 (2.0%)

425(1.3%)

 

49 (1.4%)

392 (1.3%)

 

Stroke

223 (0.7%)

9 (1.1%)

214 (0.7%)

 

32 (0.9%)

191 (0.6%)

 

Family risk of CV disease

15,692 (46.7%)

414 (52.7%)

15,278 (46.6%)

**

2,017 (56.2%)

13,675 (45.6%)

**

Framingham risk score 2

9 (4 to 13)

11 (7 to 16)

8 (4 to 13)

 

11 (7 to 15)

8 (3 to 13)

 

Weight 1 (kg)

76 (14)

77 (14)

76 (14)

 

77 (13)

76 (14)

 

BMI 2 (kg/m 2 )

25.6 (23.5 to 28.1)

26.3 (24.3 to 29.0)

25.6 (23.4 to 28.1)

**

26.4 (24.2 to 29.0)

25.4 (23.3 to 27.8)

**

Waist circumference 1 (cm)

85 (11)

86 (11)

85 (11)

*

86 (11)

85 (11)

**

Hip circumference 1 (cm)

102 (8)

103 (8)

102 (8)

**

103 (8)

101 (6)

**

Waist/hip ratio 1

0.84 (0.08)

0.84 (0.08)

0.84 (0.08)

 

0.83 (0.07)

0.84 (0.08)

**

Systolic blood pressure 2 (mmHg)

131 (120 to 144)

133 (122 to 146)

131 (120 to 144)

*

133 (122 to 147)

131 (120 to 143)

**

Diastolic blood pressure 1 (mmHg)

79 (11)

80 (11)

79 (11)

*

81 (11)

79 (11)

**

Serum cholesterol 1 (mmol/L)

5.8 (1.2)

6.0 (1.2)

5.8 (1.2)

**

6.1 (1.2)

5.8 (1.2)

**

HDL cholesterol 1 (mmol/L)

1.40 (0.39)

1.37 (0.39)

1.40 (0.39)

 

1.44 (0.40)

1.39 (0.38)

**

Serum triglycerides 2 (mmol/L)

1.40 (0.98 to 2.07)

1.51 (1.10 to 2.24)

1.40 (0.97 to 2.06)

**

1.46 (1.02 to 2.12)

1.37 (0.95 to 2.04)

**

  1. 1Values are mean (standard deviation) or numbers (%), or 2median (interquartile range). Non-respondents were excluded. BMI, body mass index; CVD, cardiovascular disease; HDL, high density lipoprotein; MI, myocardial infarction; OA, osteoarthritis; RA, rheumatoid arthritis. *P-value <0.05, **P-value <0.001, comparing individuals who developed RA and did not develop RA, or comparing individuals who developed OA and did not develop OA. All blood samples were non-fasting.
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Arthritis Research & Therapy

ISSN: 1478-6362

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