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Table 1 Genotype and allele association analysis of seven single nucleotide polymorphisms (SNPs) in samples of AS in Shandong and rs1128334 in Ningxia

From: ETS1 variants confer susceptibility to ankylosing spondylitis in Han Chinese

Population SNPs Position Genotype/allele Patients, number (%) Controls, number (%) Odds ratio 95% CI P- value P*
  rs12574073 128319478 CC 423 (42.7) 401 (47.8) 1    
    CT 457 (46.1) 356 (41.8) 1.217 1.002, 1.478 0.192  
    TT 111 (11.2) 89 (10.4) 1.182 0.867, 1.613   
    C 1,303 (65.7) 1,170 (68.7) 1    
    T 679 (34.3) 534 (31.3) 1.142 0.994, 1.311 0.062  
  rs1128334 128328959 GG 417 (42.2) 528 (48.0) 1    
    AG 457 (46.3) 471 (42.8) 1.229 1.024, 1.473 0.018  
    AA 114 (11.5) 101 (9.2) 1.429 1.062, 1.923   
    G 1,291 (65.3) 1,527 (69.4) 1    
    A 685 (34.7) 673 (30.6) 1.204 1.058, 1.371 0.005 0.035
  rs4937333 128330520 TT 183 (18.2) 177 (15.6) 1    
    CT 483 (48.0) 535 (42.3) 0.873 0.687, 1.111 0.160  
    CC 341 (33.8) 420 (37.1) 0.785 0.611, 1.010   
    T 849 (42.2) 889 (39.3) 1    
    C 1165 (57.8) 1375 (60.7) 0.887 0.785, 1.003 0.057  
Shandong rs4254089 128366221 CC 64 (6.3) 66 (5.9) 1    
    CT 356 (35.1) 365 (32.9) 1.006 0.692, 1.461 0.478  
    TT 595 (58.6) 680 (61.2) 0.902 0.629, 1.295   
    C 484 (23.8) 497 (22.4) 1    
    T 1546 (76.2) 1725 (77.6) 0.920 0.798, 1.062 0.259  
  rs7951925 128379964 AA 84 (8.3) 109 (9.7) 1    
    AG 420 (41.4) 444 (39.6) 1.227 0.896, 1.681 0.433  
    GG 510 (50.3) 569 (51.7) 1.163 0.854, 1.584   
    A 588 (29.0) 662 (29.5) 1    
    G 1,440 (71.0) 1,582 (70.5) 1.025 0.898, 1.169 0.736  
  rs7116578 128388773 AA 869 (85.9) 970 (86.3) 1    
    AG 133 (13.1) 145 (12.9) 1.024 0.795, 1.318 0.884  
    GG 10 (1.0) 9 (0.8) 1.240 0.502, 3.066   
    A 1,871 (92.4) 2,085 (92.7) 1    
    G 153 (7.6) 163 (7.3) 1.046 0.832, 1.316 0.726  
  rs4937342 128398309 TT 903 (89.8) 993 (90.2) 1    
    TG 101 (10.0) 102 (9.3) 1.089 0.815, 1.455 0.368  
    GG 2 (0.2) 6 (0.5) 0.367 0.074, 1.821   
    T 1,907 (94.8) 2,088 (94.8) 1    
    G 105 (5.2) 114 (5.2) 1.008 0.768, 1.324 1.000  
Ningxia rs1128334 128328959 GG 135 (38.4) 190 (47.5) 1    
    AG 168 (47.7) 166 (41.5) 1.424 1.047, 1.938 0.038  
    AA 49 (13.9) 44 (11.0) 1.576 0.986, 2.490   
    G 438 (62.2) 546 (68.2) 1    
    A 266 (37.8) 254 (31.8) 1.305 1.055, 1.615 0.015  
  1. *Adjusted P-value after Bonferroni correction.