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Table 2 Correlation of 14-3-3η with clinical and serological measures in two cohorts of patients with rheumatoid arthritis a

From: 14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

Cohort Variable, score or titres DAS28 CRP RF ACPA
A DAS28     Pearson product–moment correlation (r)
  CRP 0.12    
  RF 0.22 -0.13   
  ACPA -0.14 0.20 0.27  
  14-3-3η 0.18 0.20 0.43b 0.31c
B
  DAS28     Pearson product–moment correlation (r)
  CRP 0.46d    
  RF -0.06 -0.02   
  ACPA -0.17 -0.14 0.17  
  14-3-3η -0.03 -0.09 0.03 -0.07
  1. aACPA, Anticitrullinated protein antibody; CRP, C-reactive protein DAS28: Disease Activity Score in 28 joints; RF: rheumatoid factor. bP < 0.01; cP ≤ 0.05; dP < 0.001. Cohort A is the University of Sherbrooke early rheumatoid arthritis cohort at the baseline time point (n = 33). Cohort B is the Behandel Strategieën (BeSt) study cohort of patients with established RA at the year 3 time point (n = 40).