14-3-3η is a novel mediator associated with the pathogenesis of rheumatoid arthritis and joint damage

Table 2 Correlation of 14-3-3η with clinical and serological measures in two cohorts of patients with rheumatoid arthritis ^a

Cohort	Variable, score or titres	DAS28	CRP	RF	ACPA
A	DAS28				Pearson product–moment correlation (r)
	CRP	0.12
	RF	0.22	-0.13
	ACPA	-0.14	0.20	0.27
	14-3-3η	0.18	0.20	0.43^b	0.31^c
B
	DAS28				Pearson product–moment correlation (r)
	CRP	0.46^d
	RF	-0.06	-0.02
	ACPA	-0.17	-0.14	0.17
	14-3-3η	-0.03	-0.09	0.03	-0.07

^aACPA, Anticitrullinated protein antibody; CRP, C-reactive protein DAS28: Disease Activity Score in 28 joints; RF: rheumatoid factor. ^bP < 0.01; ^cP ≤ 0.05; ^dP < 0.001. Cohort A is the University of Sherbrooke early rheumatoid arthritis cohort at the baseline time point (n = 33). Cohort B is the Behandel Strategieën (BeSt) study cohort of patients with established RA at the year 3 time point (n = 40).

ISSN: 1478-6362