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Table 2 Surrogate markers in nine patients who were classified with granulomatosis with polyangiitis using these markers

From: Classification and characteristics of Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception cohort study

  Number of patients
(MPO-ANCA/PR3-ANCAa)
X-ray evidence of fixed pulmonary infiltrates, nodules, or cavitations present for >1 month 1 (1/0)
Bronchial stenosis 0 (0/0)
Bloody nasal discharge and crusting for 1 month or nasal ulceration 1b (0/1)
Chronic sinusitis, otitis media, or mastoiditis for >3 months 7c (4/5)
Retro-orbital mass or inflammation (pseudotumor) 0 (0/0)
Subglottic stenosis 1 (0/1)
Saddle nose deformity/destructive sinonasal disease 1 (0/1)
  1. ANCA, antineutrophil cytoplasmic antibody; MPO, myeloperoxidase; PR3, proteinase-3. aMPO-ANCA/PR3-ANCA, anti-myeloperoxidase antibody-positive versus anti-proteinase-3 antibody-positive patients. bOne patient had bloody nasal discharge and crusting and chronic sinusitis, and another patient had subglottic stenosis and saddle nose deformity. cFive patients with chronic sinusitis, three patients with otitis media, and no patients with mastoiditis.