| |
JIA-associated genes with correlated expression data that lie within the minimal essential network (MEN)
|
Dapple P-value
|
|---|
|
RF-ve polyarticular JIA compared with controls
|
KSR1
|
0.0088
|
|
Oligoarticular JIA compared with controls
|
PTPN2
|
0.0112
|
|
Oligoarticular compared with RF-ve polyarticular JIA
|
STAT1
|
0.0002
|
- Genes present within the MEN which also show altered gene expression in either rheumatoid-negative (RF-ve) polyarticular juvenile idiopathic arthritis (JIA) compared with controls, oligoarticular JIA compared with controls, or between oligoarticular compared with RF-ve polyarticular JIA are listed. Presence in the MEN indicates functional priority and the Disease association protein-protein link evaluator (Dapple) P-value assesses the statistical significance of network connectivity compared to what would be expected by chance.
