Table 2 The haplotype frequencies of NR1H3 gene
Haplotype | SLE | NC | SLE versus NC | ||
|---|---|---|---|---|---|
(n = 300) | (n = 217) | P value | OR (95% CI) | ||
HT1 | +/+ | 109 (36.3%) | 103 (47.5%) | co : 0.033 | 0.727 (0.542 ~ 0.974) |
[TTGG] | +/- | 169 (56.3%) | 99 (45.6%) | do : 0.808 | 0.956 (0.681 ~ 1.349) |
-/- | 22 (7.3%) | 15 (6.9%) | re : 0.012 | 0.796 (0.666 ~ 0.951) | |
HT2 | +/+ | 16 (5.3%) | 15 (6.9%) | co : 0.255 | 0.847 (0.636 ~ 1.128) |
[CTGG] | +/- | 111 (37.0%) | 87 (40.1%) | do : 0.280 | 0.908 (0.761 ~ 1.082) |
-/- | 173 (57.7%) | 115 (53.0%) | re : 0.507 | 0.884 (0.614 ~ 1.273) | |
HT3 | +/+ | 2 (0.7%) | 0 (0.0%) | co : 0.008 | 2.739 (1.304 ~ 5.751) |
[TCGG] | +/- | 30 (10.0%) | 9 (4.1%) | do : 0.009 | 1.662 (1.134 ~ 2.435) |
-/- | 268 (89.3%) | 208 (95.9%) | re : 0.999 | 36085.247 (0.000 ~ NA) | |
HT others | +/+ | 3 (1.0%) | 0 (0.0%) | co : <0.001 | 8.375 (2.557 ~ 27.431) |
+/- | 30 (10.0%) | 3 (1.4%) | do : <0.001 | 2.984 (1.641 ~ 5.427) | |
-/- | 267 (89.0%) | 214 (98.6%) | re : 0.999 | 32475.263 (0.000 ~ NA) | |