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Table 3 Serum cytokine levels in IgG4-RD, pSS patients and HC

From: B cell subsets and dysfunction of regulatory B cells in IgG4-related diseases and primary Sjögren’s syndrome: the similarities and differences

  HC IgG4-RD pSS IgG4-RD versus HC pSS versus HC IgG4-RD versus pSS
(n = 24) (n = 28) (n = 28) P- value P- value P- value
IL-4, pg/mL 1.69 ± 1.46 6.54 ± 5.67 6.52 ± 6.14 <0.001 <0.001 0.931
IL-5, pg/mL 1.34 ± 1.03 1.48 ± 1.51 2.23 ± 3.16 0.932 0.776 0.965
IL-6, pg/mL 0.68 ± 0.39 2.14 ± 1.66 1.35 ± 1.40 <0.001 0.002 0.009
IL-10, pg/mL 3.22 ± 1.40 10.67 ± 5.50 11.59 ± 7.90 <0.001 <0.001 0.697
IL-13, pg/mL 3.18 ± 2.61 3.99 ± 6.15 10.05 ± 13.99 0.524 0.016 0.013
IL-17A, pg/mL 0.24 ± 0.15 0.40 ± 0.57 1.10 ± 1.37 0.482 <0.001 0.001
IFN-γ, pg/mL 1.02 ± 0.81 2.23 ± 1.56 3.20 ± 3.15 0.002 0.002 0.493
TGF-β, ng/mL 17.73 ± 4.81 16.94 ± 7.73 14.16 ± 5.66 0.643 0.006 0.035
BAFF, ng/mL 0.70 ± 0.42 2.60 ± 2.80 2.31 ± 2.65 <0.001 <0.001 0.236
  1. Values are shown as mean ± SD. IgG4-RD, IgG4-related disease; pSS, primary Sjögren’s syndrome; HC, healthy controls.
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Arthritis Research & Therapy

ISSN: 1478-6362

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