| |
HC
|
IgG4-RD
|
pSS
|
IgG4-RD versus HC
|
pSS versus HC
|
IgG4-RD versus pSS
|
|---|
|
(n = 24)
|
(n = 28)
|
(n = 28)
|
P- value
|
P- value
|
P- value
|
|---|
|
IL-4, pg/mL
|
1.69 ± 1.46
|
6.54 ± 5.67
|
6.52 ± 6.14
|
<0.001
|
<0.001
|
0.931
|
|
IL-5, pg/mL
|
1.34 ± 1.03
|
1.48 ± 1.51
|
2.23 ± 3.16
|
0.932
|
0.776
|
0.965
|
|
IL-6, pg/mL
|
0.68 ± 0.39
|
2.14 ± 1.66
|
1.35 ± 1.40
|
<0.001
|
0.002
|
0.009
|
|
IL-10, pg/mL
|
3.22 ± 1.40
|
10.67 ± 5.50
|
11.59 ± 7.90
|
<0.001
|
<0.001
|
0.697
|
|
IL-13, pg/mL
|
3.18 ± 2.61
|
3.99 ± 6.15
|
10.05 ± 13.99
|
0.524
|
0.016
|
0.013
|
|
IL-17A, pg/mL
|
0.24 ± 0.15
|
0.40 ± 0.57
|
1.10 ± 1.37
|
0.482
|
<0.001
|
0.001
|
|
IFN-γ, pg/mL
|
1.02 ± 0.81
|
2.23 ± 1.56
|
3.20 ± 3.15
|
0.002
|
0.002
|
0.493
|
|
TGF-β, ng/mL
|
17.73 ± 4.81
|
16.94 ± 7.73
|
14.16 ± 5.66
|
0.643
|
0.006
|
0.035
|
|
BAFF, ng/mL
|
0.70 ± 0.42
|
2.60 ± 2.80
|
2.31 ± 2.65
|
<0.001
|
<0.001
|
0.236
|
- Values are shown as mean ± SD. IgG4-RD, IgG4-related disease; pSS, primary Sjögren’s syndrome; HC, healthy controls.
