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Table 1 Characteristics of the study population (n = 186)

From: Elevated C-reactive protein is associated with lower increase in knee muscle strength in patients with knee osteoarthritis: a 2-year follow-up study in the Amsterdam Osteoarthritis (AMS-OA) cohort

 

Baseline

2-year follow-up

 

Number

 

Number

 

Age, years

186

61 (7.3)

-

-

Female, n (%)

186

127 (68)

-

-

Radiographic OA-KL score ≥2, n (%)

184

130 (70)

186

123 (66)

WOMAC pain score, 0-20

183

7.9 (3.8)

185

7.0 (4.3)ª

WOMAC stiffness score, 0-8

179

3.7 (1.7)

186

3.5 (2.0)ª

WOMAC physical function score, 0-68

183

28.6 (13.4)

186

27.0 (15.3)

Comorbidities count, CIRS ≥2

184

0.8 (1.0)

175

1.1 (1.0)ª

NSAIDs, yes, n (%)

185

30 (16)

186

38 (20)

Body mass index, kg/m2

185

29.3 (5.5)

186

29.3 (5.4)

Physical activity ≥30 minutes, times per week

-

No information

183

3.0 (1.3)

PT treatment during the past 2 years, n (%)

-

No information

186

149 (80)

Knee muscle strengthb, Nm/kg

177

0.88 (0.4)

183

0.95 (0.4)ª

Inflammatory markers

    

 C-reactive protein, mg/L

183

 

184

 

 Median, IQR

 

2 (1-4)

 

2 (1-3)

 Mean, SD

 

3.4 (5.4)

 

2.9 (3.1)

 >3 mg/L, n (%)

 

50 (27)

 

45 (24)

 ESR, mm/hour

183

 

186

 

 Median, IQR

 

9 (5-15)

 

7 (4-12)

 Mean, SD

 

11.6 (8.9)

 

9.5 (8.4)ª

 ≥20 mm/hour, n (%)

 

34 (18)

 

25 (13)

  1. Values are presented as mean ± standard deviation (SD), unless stated otherwise. ªSignificant difference between baseline and follow-up assessment (P <0.05). bMean quadriceps and hamstring muscles in osteoarthritis (OA) knees. CIRS, Cumulative Illness Rating Scale; ESR, erythrocyte sedimentation rate; IQR, interquartile range; KL, Kellgren-Lawrence; NSAID, non-steroidal anti-inflammatory drug; PT, physiotherapy; WOMAC, Western Ontario and McMaster Universities Osteoarthritis.