Monitoring the effects of dexamethasone treatment by MRI using in vivo iron oxide nanoparticle-labeled macrophages

Table 1 Naked SPION and SPION characterization

Particles	Medium	Concentration, mg _Fe/ml	Cores size, nm	Particle size (PDI), nm	Zeta potential at pH 7, mV	PVA/Fe ratio, mg _PVA/mg _Fe	Saturation magnetization, EMU/g
Naked SPION	HNO₃ 10 mM	10	7.2 ± 2.5	14 ± 2 (0.25)	0 ± 3	0	54
SPION	HNO₃ 5 mM	5	7.2 ± 2.5	25 ± 3 (0.20)	+16 ± 3	9	54

Core sizes: diameter of SPION measured by transmission electron microscopy (TEM) image analyses; particle size: hydrodynamic number-weighted diameter measured by PCS and given with polydispersity index
SPION, superparamagnetic iron oxide nanoparticles; PDI, polydispersity index.
+/- are standard error for the core size and +/SD for the rest the parameters (Particle size and Zeta potential).

ISSN: 1478-6362