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Table 1 Demographic characteristics of the 285 patients in this study

From: Anti-MDA5 autoantibodies in juvenile dermatomyositis identify a distinct clinical phenotype: a prospective cohort study

  All JDM patients, n = 285 Anti-MDA5-positive patients, n = 21
Female, number (%) 206 (72) 15 (71)
Caucasian, number (%) 220 (78) 16 (76)b
Diagnosis, number (%) a   
  Dermatomyositis 242 (85) 21 (100)
  Polymyositis 1 (0.4) 0
  Overlap 33 (12) 0
Age at disease onset, years, median (IQR) 6.3 (IQR 4 to 10) 6.6 (IQR 4 to 10)
Length of follow up, years, median (IQR) 9 (IQR 5 to 12) 8 (IQR 5 to 11)
Highest ever CK, u/l, median (IQR) 220 (IQR 111 to 1132) 129 (88 to 157)
  1. aNine patients were classified as having focal myositis or other idiopathic inflammatory myopathy; bOne Black-African patient, one Indian patient, one Pakastani patient and two patients from other ethnic groups. All anti-MDA5 autoantibody-positive patients had juvenile dermatomyositis (JDM). Otherwise, demographic data did not differ significantly between anti-MDA5 antibody positive patients and the overall cohort. IQR, interquartile range; CK, creatine kinase.