Skip to main content

Table 2 Relationship between change in WOMAC and change in BML size

From: The clinical significance, natural history and predictors of bone marrow lesion change over eight years

  Univariable Multivariablea Femalesa Malesa
Total 1.74 (0.65, 2.84) 1.53 (0.37, 2.70) 0.63 (-0.93, 2.20) 2.53 (0.76, 4.30)
Offspring 2.68 (1.22, 4.13) 2.50 (0.96, 4.05) 2.25 (0.10, 4.41) 3.06 (0.88, 5.24)
Controls -0.05 (-1.72, 1.62) -0.39 (-2.23, 1.44) -0.77 (-3.51, 1.98) 1.44 (-1.25, 4.14)
  1. Data presented as beta coefficient (95% confidence interval). Values are the change in WOMAC pain score per cm2 change in BML size. An interaction between offspring–control status and change in BML size (P = 0.01) as well as sex and change in BML size (P = 0.08) on change in pain was present. BML, bone marrow lesion; WOMAC, Western Ontario and McMasters Universities Arthritis Index. Bold data indicate P <0.05. aAdjusted for age, sex, body mass index, leg strength, and radiographic osteoarthritis.