| Â | Univariable | Multivariablea | Femalesa | Malesa |
|---|
Total |
1.74 (0.65, 2.84)
|
1.53 (0.37, 2.70)
| 0.63 (-0.93, 2.20) |
2.53 (0.76, 4.30)
|
Offspring |
2.68 (1.22, 4.13)
|
2.50 (0.96, 4.05)
|
2.25 (0.10, 4.41)
|
3.06 (0.88, 5.24)
|
Controls | -0.05 (-1.72, 1.62) | -0.39 (-2.23, 1.44) | -0.77 (-3.51, 1.98) | 1.44 (-1.25, 4.14) |
- Data presented as beta coefficient (95% confidence interval). Values are the change in WOMAC pain score per cm2 change in BML size. An interaction between offspring–control status and change in BML size (P = 0.01) as well as sex and change in BML size (P = 0.08) on change in pain was present. BML, bone marrow lesion; WOMAC, Western Ontario and McMasters Universities Arthritis Index. Bold data indicate P <0.05. aAdjusted for age, sex, body mass index, leg strength, and radiographic osteoarthritis.
