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Table 1 Serious infections requiring hospitalization in SLE and LN patients, stratified by sociodemographic factors and the SLE comorbidity index

From: Sociodemographics and epidemiology of serious infections requiring hospitalization among adults with systemic lupus erythematosus and lupus nephritis, 2000 to 2006

  Prevalent SLE cohort (n= 43,274) Prevalent LN cohort (n= 8,096)
Total number of patients with a serious infection, n (%) 7,823 (18.1) 3,035 (37.5)
Total number of episodes of serious infections 17,055 7,486
Age, n (%)   
  18 to 34 2,738 (35) 1,489 (49.1)
  35 to 50 3,385 (43.3) 1,063 (35)
  51 to 65 1,700 (21.7) 483 (15.9)
Sex, n (%)   
  Female 7,211 (92.2) 2,684 (88.4)
  Male 612 (7.8) 351 (11.6)
Race/ethnicity, n (%)   
  White 2,613 (33.4) 674 (22.2)
  African American 3,465 (44.3) 1,568 (51.7)
  Hispanic 915 (11.7) 429 (14.1)
  Asian 272 (3.5) 148 (4.9)
  Native American 141 (1.8) 59 (5.2)
  Other 417 (5.3) 157 (5.2)
Region   
  Northeast 1,502 (19.2) 578 (19.0)
  South 3,187 (40.7) 1,198 (39.5)
  Midwest 1,736 (22.2) 748 (24.7)
  West 1,398 (17.9) 511 (16.8)
SES tertile   
  SES 1 (lowest) 2,525 (32.3) 937 (30.9)
  SES 2 2,402 (30.7) 1,001 (33.0)
  SES 3 (highest) 2,441 (31.2) 935 (30.8)
SLE specific risk indexa   
  Index 1 (lowest) 2,298 (29.4) 1,164 (38.4)
  Index 2 3,478 (44.5) 864 (28.5)
  Index 3 (highest) 2,047 (26.2) 1,007 (33.2)
  1. aSLE-specific modification of the Charlson comorbidity index developed by MM Ward and more predictive of in-hospital mortality than the Charlson index among SLE patients.