Table 1 Serious infections requiring hospitalization in SLE and LN patients, stratified by sociodemographic factors and the SLE comorbidity index
| Â | Prevalent SLE cohort (n= 43,274) | Prevalent LN cohort (n= 8,096) |
|---|---|---|
Total number of patients with a serious infection, n (%) | 7,823 (18.1) | 3,035 (37.5) |
Total number of episodes of serious infections | 17,055 | 7,486 |
Age, n (%) | Â | Â |
  18 to 34 | 2,738 (35) | 1,489 (49.1) |
  35 to 50 | 3,385 (43.3) | 1,063 (35) |
  51 to 65 | 1,700 (21.7) | 483 (15.9) |
Sex, n (%) | Â | Â |
  Female | 7,211 (92.2) | 2,684 (88.4) |
  Male | 612 (7.8) | 351 (11.6) |
Race/ethnicity, n (%) | Â | Â |
  White | 2,613 (33.4) | 674 (22.2) |
  African American | 3,465 (44.3) | 1,568 (51.7) |
  Hispanic | 915 (11.7) | 429 (14.1) |
  Asian | 272 (3.5) | 148 (4.9) |
  Native American | 141 (1.8) | 59 (5.2) |
  Other | 417 (5.3) | 157 (5.2) |
Region | Â | Â |
  Northeast | 1,502 (19.2) | 578 (19.0) |
  South | 3,187 (40.7) | 1,198 (39.5) |
  Midwest | 1,736 (22.2) | 748 (24.7) |
  West | 1,398 (17.9) | 511 (16.8) |
SES tertile | Â | Â |
  SES 1 (lowest) | 2,525 (32.3) | 937 (30.9) |
  SES 2 | 2,402 (30.7) | 1,001 (33.0) |
  SES 3 (highest) | 2,441 (31.2) | 935 (30.8) |
SLE specific risk indexa | Â | Â |
  Index 1 (lowest) | 2,298 (29.4) | 1,164 (38.4) |
  Index 2 | 3,478 (44.5) | 864 (28.5) |
  Index 3 (highest) | 2,047 (26.2) | 1,007 (33.2) |