Skip to main content

Table 2 Association of endostatin levels and capillaroscopy findings

From: Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers

  Status Median (ng/ml) Range (ng/ml) P value
Avascular areas Present (n = 14) 20 4–750 0.13
  Absent (n = 28) 17 0–750  
Giant capillaries Present (n = 19) 6 0–750 0.02
  Absent (n = 23) 20 4–750  
Hemorrhages Present (n = 15) 18 0–750 0.19
  Absent (n = 27) 20 4–750  
Pericapillary edema Present (n = 37) 18 0–750 0.18
  Absent (n = 5) 20 6–650  
  1. Patients without giant capillaries showed significantly higher levels of endostatin than patients with giant capillaries. Similarly, there was a trend towards higher levels of endostatin in patients with avascular areas and in patients that did not have nailfold microhemorrhages and pericapillary edema.