|
Effect*
|
---|
| | | |
Cartilage
|
---|
Gene
|
Edema
|
Synovitis
|
WBC
|
Synthesis
|
Degn
|
---|
IL-1Ra
|
0
|
0/-
|
-
|
NT
|
-
|
TNFRa
|
0
|
0
|
0/-
|
NT
|
0
|
IL-1Ra + TNFRa
|
-
|
-
|
-
|
NT
|
-
|
vIL-10
|
-
|
-
|
-
|
+
|
-
|
IGF-1
|
0
|
0
|
0
|
+
|
0
|
- *0, No effect; -, inhibition; +, stimulation; NT, nottested; WBC, white blood cell infiltrate into the synovial fluid;Degn, degradation; IL-1Ra, interleukin-1 receptorantagonist; TNFRa, tumor necrosis factor receptor antagonist; vIL-10, viralinterleukin-10; IGF, insulin-like growth factor.