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Table 1 Ratio of cell populations between DBA/1 wildtype spleen and IL-10-/- spleen in IL-10 deficient micea

From: Collagen-induced arthritis is exacerbated in IL-10-deficient mice

 

DBA/1 wildtype

IL-10-/-

 

Cells

%

n × 107

%

n × 107

Ratio of cell number, IL-10-/-/WT

CD3

16.4 ± 0.68

1.3 ± 0.4

9.7 ± 3.8

1.4 ± 0.6

1.07

B220

63.7 ± 2.5

5.3 ± 1.6

31.8 ± 3.3

4.5 ± 0.5

0.84

CD11c

4.1 ± 0.4

0.3 ± 0.1

2.33 ± 0.7

0.3 ± 0.1

0.94

CD11b

10.7 ± 2.0

0.9 ± 0.1

22.5 ± 3.7

3.2 ± 0.8*

3.7

  1. a The percentage of CD3, B220, CD11c, and CD11b cells was determined by flow cytometry as described in Materials and methods, and the exact number of cells calculated based on the total number of splenocytes. Values are presented as the mean ± standard deviation of three mice. The ratio was calculated as the number of IL-10-/- cells divided by the number of DBA/1 wildtype cells. * Significantly different (P < 0.05 in comparison with DBA/1 wildtype).
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Arthritis Research & Therapy

ISSN: 1478-6362

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