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Figure 3 | Arthritis Res Ther

Figure 3

From: The relationship between predicted peptide–MHC class II affinity and T-cell activation in a HLA-DRβ1*0401 transgenic mouse model

Figure 3

The ability of a peptide to induce proliferation and IFN-γ production in DR4-IE transgenic mice correlates with the DR4 binding score. (a) Correlation between DR4 binding score and T-cell proliferation. Data were compiled from experiments described in Fig. 2 using a peptide concentration of 10 μg/ml and represent the average stimulation index ± SEM. (b) Correlation between DR4 binding score and IFN-γ production. Data were compiled from experiments described in Fig. 4 using a peptide concentration of 10 μg/ml and represent the average IFN-γ response ± SD. Correlation coefficients are indicated as r2.

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