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Figure 2 | Arthritis Res Ther

Figure 2

From: The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus

Figure 2

VH gene family usage. (a) Comparison of VH gene family usage of functional rearrangements found in the combined germinal centers (GCs) and B-cell clusters. VH gene family usage differed significantly from the expected frequencies, assuming each germline gene is equally likely to form a viable rearrangement (P < 0.01). VH1 was significantly under-expressed (P = 0.0066) and VH5 over-expressed (P = 0.046). (b) D gene family use. (c) JH family usage differed significantly from expected (P = 0.0015).

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