Figure 5
From: The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus
![Figure 5](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Far627/MediaObjects/13075_2002_Article_625_Fig5_HTML.jpg)
Clonal genealogical trees constructed from sequence data from germinal centre (GC) A, GC B and cluster C. Numbers in bold indicate the minimum number of mutations required between each sequence. The bracketed figures represent silent mutations. The dashed circle shown in cluster C represents a hypothetical intermediate that was not actually found among the sequences. GC A contained two highly mutated B cell clones represented as (a) and (b).