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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis

Figure 4

Analyses of B cells from paired samples of blood (B) and synovialtissue from both the right (R) and left (L) hips of the same rheumatoidarthritis patient. Results using both the genomic DNA-based assay and thecomplementary (c)DNA-based assay for the three major immunoglobulin isotypes(M, G, and A) are shown. R, clones that are restricted to the right hip joint;L, clones that are restricted to the left hip joint; R+L, clones that arecommon to both the right and left hip joints.

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