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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

Figure 4

Expression of CD69 and human leucocyte antigen (HLA) DR byB8-RAKFKQLL-specific T cells in peripheral blood and synovial fluid frompatient RhA7. Samples of peripheral blood mononuclear cells (dashed lines) andsynovial fluid mononuclear cells (continuous lines) were stained with theB8/RAKFKQLL tetramer, with anti-CD8 and with monoclonal antibodies specific forCD69 or HLA-DR; 200 000 live cells were analyzed, and expression of CD69 andHLA-DR by the populations of CD8+ B8/RAKFKQLL tetramer reactive cells is shown.FITC, fluorescein isothiocyanate

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