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Table 2 Frequency of, and tumour necrosis factor secretion by, Synovial Tcells specific for cytomegalovirus

From: Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes

   TNF response (pg/ml)
Patient HLA-A2-NLV+/CD8+ T cells (%) 104 105
RA3 0.2 3 45
RA11 2.3 21 102
RA14 0.5 10 61
RA15 13.9 60 70
  1. Tumour necrosis factor (TNF) response was estimated by titratingthe mononuclear cells after short-term incubation with COS cells transfectedwith human leucocyte antigen (HLA)-A2 and pp65 complementary DNA, as describedby Scotet et al [16].