Figure 1

First scientific description of local bone erosion in arthritis. (a) Photograph of Anton Weichselbaum, Chairman of Pathology at the University of Vienna from 1893 to 1916. (b) Title page of the manuscript published by Anton Weichselbaum in the Archives for Pathology, Anatomy, Physiology and Clinical Medicine in 1878. (c) Title of the manuscript, meaning "The finer changes of joint cartilage in fungous synovitis and caries of the joint-ends". Fungous synovitis was an old term for rheumatoid arthritis, which referred to excessive synovial hyperplasia. Caries of the joint ends was the first scientific description of local bone erosion in rheumatoid arthritis.