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Table 1 Patient details of NP cells used within this study

From: Expression and regulation of neurotrophic and angiogenic factors during human intervertebral disc degeneration

Code

Source

Age

IVD level

IVD intact

Average grade

Infiltrated

1

Surgical

32

L5/S1

Yes

2.0

 

2

Postmortem

45

L4/L5

Yes

2.0

 

3

Postmortem

45

L3/L4

Yes

3.0

 

4

Surgical

51

L4/L5

 

2.0

 

5

Surgical

42

L5/S1

Yes

3.0

 

6

Surgical

24

L4/L5

No

3.0

 

7

Surgical

38

L5/S1

No

3.5

 

8

Surgical

25

L4/L5

Yes

4.0

 

9

Surgical

45

L5/S1

Yes

4.0

 

10

Surgical

43

L5/S1

No

4.0

 

11

Surgical

47

L5/S1

Yes

5.3

 

12

Surgical

47

L5/S1

Yes

5.85

 

13

Surgical

26

C3/C5

 

6.0

 

14

Surgical

30

L5/S1

No

6.15

 

15

Surgical

46

L5/S1

No

6.16

 

16

Surgical

70

C5/C6

 

6.18

 

17

Surgical

65

L3/L4

No

6.5

 

18

Surgical

52

L4/L5

No

6.7

 

19

Surgical

66

L5/S1

Yes

6.85

 

20

Surgical

43

L5/S1

No

7.0

 

21

Surgical

44

L5/S1

Yes

7.0

 

22

Surgical

38

L5/S1

 

7.0

 

23

Surgical

36

L5/S1

Yes

8.0

 

24

Surgical

28

L5/S1

No

8.0

 

25

Surgical

35

L5/S1

Yes

8.0

 

26

Surgical

33

L4/L5

Yes

8.0

 

27

Surgical

37

L5/S1

Yes

8.0

 

28

Surgical

49

L4/L5

No

8.0

 

29

Surgical

29

L5/S1

No

8.0

 

30

Surgical

42

L4/L5

No

8.0

 

31

Surgical

38

L4/L5

No

8.15

 

32

Surgical

42

L5/S1

No

9.0

 

33

Surgical

38

C6/C7

No

9.0

 

34

Surgical

48

L4/L5

No

10.0

 

35

Surgical

26

L5/S1

No

11.0

 

36

Surgical

35

L4/L5

No

11.0

 

37

Surgical

49

L2/L3

No

1.0

Yes

38

Surgical

20

L4/L5

No

3.0

Yes

39

Surgical

40

L5/S1

No

3.0

Yes

40

Surgical

39

L4/L5

No

3.0

Yes

41

Surgical

42

L4/L5

No

4.0

Yes

42

Surgical

26

L4/L5

Yes

4.0

Yes

43

Surgical

31

L5/S1

No

4.0

Yes

44

Surgical

39

L5/S1

No

5.0

Yes

45

Surgical

62

L3/L4

Yes

6.0

Yes

46

Surgical

40

L5/S1

Yes

7.0

Yes

47

Surgical

33

L5/S1

Yes

9.0

Yes

48

Surgical

45

L4/L5

No

3.0

 

49

Surgical

27

L5/S1

No

3.0

 

50

Surgical

21

L5/S1

No

7.0

Yes

51

Surgical

38

L4/L5

No

7.0

Yes

52

Surgical

 

L5/S1

No

8.0

 

53

Surgical

28

L4/L5

Yes

9.0

 
  1. Eight patient samples were classified as nondegenerate (grade 0 to 3), 12 patient samples were classed as moderately degenerate (grade 4 to 6), 20 IVD samples were classified as severely degenerate (grade 7 to 12) and 12 patients had evidence of infiltration. Note, samples 2 and 3 are from the same postmortem individual. Patients in bold were used in cytokine treatment experiments. Samples 48, 50, 51, 52 and 53 were used for interleukin-1β treatments. Samples 49, 51 and 52 were used in interleukin-6 and tumour necrosis factor alpha treatments. NP, nucleus pulposus; IVD, intervertebral disc.