Genotype-phenotype correlation of 116 Japanese familial Mediterranean fever (FMF) patients. (A) Age at onset of each genotype in years (y.o.). (B) Frequency of attacks in each genotype (times per year). (C) Duration of attacks in each genotype (days). (D) Efficacy of colchicine therapy in each genotype. Complete response means asymptomatic, Good response means occasional attacks.