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Table 6 Principal component analysis of nonexpanded chondrocytes

From: Cytokine profiles in the joint depend on pathology, but are different between synovial fluid, cartilage tissue and cultured chondrocytes

Mediator Cluster
1 2 3 4 5
OSM 0.954     
IL-10 0.932     
IL-1β 0.889     
MCP1 0.859     
IL-1α 0.804     
IL-1RA 0.700     
Leptin   0.880    
HGF   0.857    
IL-13   0.817    
IL-4   0.772    
IL-7   0.754    
IFNγ   0.661    
IL-8    −0.856   
IL-6    0.808   
RANTES    0.682   
bFGF     0.764  
Adiponectin     0.750  
TNFα     0.667  
VEGF      0.741
LIF      0.619
IL-6R      0.588
Eigenvalues 7.1 3.9 2.5 1.6 1.1
Variance explained (%) 34 19 12 8 5
Cronbach’s alpha 0.152 0.392 −3.235 0.032 0.068
  1. bFGF, basic fibroblast growth factor; HGF, hepatocyte growth factor; IFNγ, interferon gamma; IL, interleukin; LIF, leukaemia inhibitory factor; MCP1, monocyte chemotactic factor 1; OSM, oncostatin M; RANTES, regulated upon activation normal T cell expressed and presumably secreted; TNFα, tumour necrosis factor alpha; VEGF, vascular endothelial growth factor.