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Table 3 Cluster analysis variables compared across clusters a

From: OMERACT-based fibromyalgia symptom subgroups: an exploratory cluster analysis

Measure

Cluster 1b(n = 150)

Cluster 2c(n = 171)

Cluster 3d(n = 136)

Cluster 4e(n = 124)

P-valuef

MFI physical fatigue

12.5 (3.7)

17.1 (2.4)

15.5 (2.8)

18.5 (1.7)

<0.0001

MOS-Sleep Problems Index II

42.4 (16.5)

56.2 (17.2)

53.5 (15.4)

70.8 (15.5)

<0.0001

BPI pain severity

3.6 (1.4)

5.5 (1.4)

4.7 (1.5)

6.6 (1.2)

<0.0001

MASQ

80.1 (15.7)

88.5 (16.9)

98.8 (17.8)

119.5 (17.4)

<0.0001

FIQ function

7.1 (4.8)

16.2 (5.7)

12.9 (5.2)

21.5 (4.0)

<0.0001

FIQ stiffness

5.0 (2.2)

8.0 (1.4)

7.2 (1.8)

8.7 (1.1)

<0.0001

POMS tension-anxiety

3.9 (3.1)

4.3 (2.6)

10.2 (3.6)

12.1 (3.8)

<0.0001

POMS Depression-Dejection

3.2 (3.2)

3.7 (2.5)

10.0 (3.7)

12.1 (4.5)

<0.0001

  1. aData are mean ± SD. BPI, Brief Pain Inventory; FIQ, Fibromyalgia Impact Questionnaire; MASQ, Multiple Ability Self-report Questionnaire; MFI, Multidimensional Fatigue Inventory; MOS-Sleep Problems Index II, Medical Outcomes Study Sleep scale; POMS, Profile of Mood States; SF-36, Medical Outcomes Study 36-item Short Form survey. bLow symptom intensity. cModerate symptoms, low negative mood. dModerate symptoms, higher negative mood and dyscognition. eHigh symptom intensity. fP-values reported are from the omnibus analysis of variance test across the four clusters. Pairwise comparisons between clusters also showed significant differences in all cases, except for the following: cluster 2 versus cluster 3 MOS-Sleep Problems Index II (P = 0.16) and cluster 1 versus cluster 2 with respect to both POMS Tension-Anxiety (P = 0.26) and Depression-Dejection (P = 0.23).