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Table 3 Cluster analysis variables compared across clusters a

From: OMERACT-based fibromyalgia symptom subgroups: an exploratory cluster analysis

Measure Cluster 1b(n = 150) Cluster 2c(n = 171) Cluster 3d(n = 136) Cluster 4e(n = 124) P-valuef
MFI physical fatigue 12.5 (3.7) 17.1 (2.4) 15.5 (2.8) 18.5 (1.7) <0.0001
MOS-Sleep Problems Index II 42.4 (16.5) 56.2 (17.2) 53.5 (15.4) 70.8 (15.5) <0.0001
BPI pain severity 3.6 (1.4) 5.5 (1.4) 4.7 (1.5) 6.6 (1.2) <0.0001
MASQ 80.1 (15.7) 88.5 (16.9) 98.8 (17.8) 119.5 (17.4) <0.0001
FIQ function 7.1 (4.8) 16.2 (5.7) 12.9 (5.2) 21.5 (4.0) <0.0001
FIQ stiffness 5.0 (2.2) 8.0 (1.4) 7.2 (1.8) 8.7 (1.1) <0.0001
POMS tension-anxiety 3.9 (3.1) 4.3 (2.6) 10.2 (3.6) 12.1 (3.8) <0.0001
POMS Depression-Dejection 3.2 (3.2) 3.7 (2.5) 10.0 (3.7) 12.1 (4.5) <0.0001
  1. aData are mean ± SD. BPI, Brief Pain Inventory; FIQ, Fibromyalgia Impact Questionnaire; MASQ, Multiple Ability Self-report Questionnaire; MFI, Multidimensional Fatigue Inventory; MOS-Sleep Problems Index II, Medical Outcomes Study Sleep scale; POMS, Profile of Mood States; SF-36, Medical Outcomes Study 36-item Short Form survey. bLow symptom intensity. cModerate symptoms, low negative mood. dModerate symptoms, higher negative mood and dyscognition. eHigh symptom intensity. fP-values reported are from the omnibus analysis of variance test across the four clusters. Pairwise comparisons between clusters also showed significant differences in all cases, except for the following: cluster 2 versus cluster 3 MOS-Sleep Problems Index II (P = 0.16) and cluster 1 versus cluster 2 with respect to both POMS Tension-Anxiety (P = 0.26) and Depression-Dejection (P = 0.23).