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Table 3 Baseline demographic and clinical features of RA and OA patients in the study of PGC-1β expression in FLS by qPCR and western blot

From: Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting extracellular signal-regulated kinase, p38 and nuclear factor-kappaB activation

Characteristic

RA patients (n = 8)

OA patients (n = 6)

Demographic

  

Age, yrs, median (range)

55 (33 to 70)

57 (51 to 68)

Female, n (%)

8 (100)

6 (100)

Disease status

  

Disease duration, mo, median (range)

78 (2 to 240)

36 (12 to 168)

ESR, mm/h, median (range)

50 (11 to 83)

18 (12 to 32)

CRP, mg/dl, median (range)

1.53 (0.02 to 4.55)

0.33 (0.08 to 1.11)

Rheumatoid factor-positive, n (%)

7 (87.5)

NA

Anti-CCP-positive, n (%)

8 (100)

NA

DAS28, median (range)

4.36 (3.06 to 5.82)

NA

Previous medications, n (%)

 

NA

Corticosteroids

3 (37.5)

NA

Methotrexate

4 (50)

NA

Leflunomide

3 (37.5)

NA

Hydroxychloroquine

2 (25)

NA

Infliximab

1 (12.5)

NA

Etanercept

1 (12.5)

NA

  1. FLS, fibrolast-like synoviocytes; ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; RF, rheumatoid factor; Anti-CCP, anti-cyclic citrullinated peptide antibodies; DAS28, disease activity score 28-joint assessment; n, number of patients; RA, rheumatoid arthritis; OA, osteoarthritis; NA, not applicable.