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Table 2 Genotype effect on serum C-reactive protein level and Disease Activity Score in 28 joints at baseline and year 1 a

From: CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients

 

Baseline CRP

Year 1 CRP

Baseline DAS28

Year 1 DAS28

SNP

β

P-value

β

P-value

β

P-value

β

P-value

rs11265257

-0.14

0.19

-0.01

0.91

-0.09

0.31

-0.06

0.49

rs1130864

0.15

0.21

0.03

0.78

0.16

0.10

0.14

0.12

rs1205

-0.26

0.03

-0.09

0.38

-0.08

0.39

-0.09

0.32

rs1800947

-0.34

0.14

-0.12

0.57

0.02

0.91

0.23

0.21

rs2808632

0.18

0.15

-0.04

0.73

-0.04

0.71

-0.08

0.40

rs3093077

-0.10

0.69

0.30

0.16

-0.26

0.21

-0.02

0.90

rs876538

0.15

0.28

-0.05

0.66

0.02

0.86

-0.02

0.87

  1. aLinear regression analysis with age, sex and treatment as covariates. CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; SNP, Single-nucleotide polymorphism.
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Arthritis Research & Therapy

ISSN: 1478-6362

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