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Table 2 Genotype effect on serum C-reactive protein level and Disease Activity Score in 28 joints at baseline and year 1 a

From: CRP genotype and haplotype associations with serum C-reactive protein level and DAS28 in untreated early rheumatoid arthritis patients

  Baseline CRP Year 1 CRP Baseline DAS28 Year 1 DAS28
SNP β P-value β P-value β P-value β P-value
rs11265257 -0.14 0.19 -0.01 0.91 -0.09 0.31 -0.06 0.49
rs1130864 0.15 0.21 0.03 0.78 0.16 0.10 0.14 0.12
rs1205 -0.26 0.03 -0.09 0.38 -0.08 0.39 -0.09 0.32
rs1800947 -0.34 0.14 -0.12 0.57 0.02 0.91 0.23 0.21
rs2808632 0.18 0.15 -0.04 0.73 -0.04 0.71 -0.08 0.40
rs3093077 -0.10 0.69 0.30 0.16 -0.26 0.21 -0.02 0.90
rs876538 0.15 0.28 -0.05 0.66 0.02 0.86 -0.02 0.87
  1. aLinear regression analysis with age, sex and treatment as covariates. CRP, C-reactive protein; DAS28, Disease Activity Score in 28 joints; SNP, Single-nucleotide polymorphism.