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Table 1 Demographic and clinical data, lupus activity (SLEDAI) and individual therapy of the patients at the time of analysis

From: Active systemic lupus erythematosus is associated with a reduced cytokine production by B cells in response to TLR9 stimulation

Patient ID

Sex

Age, y

B cells/μL blood

anti-dsDNA IgG, U/mL

SLEDAI

Treatment

Prednisolone dose, mg/d

SLE1

F

61

187

0

7

Pred

5.0

SLE2

F

31

320

0

5

Pred, MTX

5.0

SLE3

F

30

159

0

4

Pred, MMF

5.0

SLE4

F

25

132

45

8

Pred, Aza, HCQ

5.0

SLE5

F

36

216

38

8

Pred, Aza

7.5

SLE6

F

39

538

50

6

Pred, MMF

5.0

SLE7

F

22

164

0

4

Pred

5.0

SLE8

F

44

108

0

5

HCQ

0

SLE9

F

48

67

75

8

Pred, MMF

5.0

SLE10

M

20

89

50

10

Pred, Aza

5.0

SLE11

F

30

305

45

6

Pred

5.0

SLE12

F

33

468

0

5

Pred

8.0

SLE13

F

23

785

125

14

Pred, HCQ

100.0

SLE14

F

33

110

18

4

Pred, HCQ

5.0

SLE15

F

32

75

60

12

Pred, MMF

8.0

SLE16

F

37

ND

2,000

15

Pred, HCQ

25.0

SLE17

F

38

192

21

8

Pred, HCQ, MMF

7.5

SLE18

F

47

114

1,400

14

Therapy naive

0

SLE19

F

59

26

0

5

Pred, Aza

5.0

SLE20

F

30

32

1,000

5

HCQ

0

SLE21

F

51

81

200

6

Pred, Aza

7.5

SLE22

F

28

56

0

6

Ciclosporine, Pred

5.0

SLE23

F

33

98

0

6

Pred, Aza

5.0

SLE24

F

32

155

17.5

18

Cylophosphamide, Pred

7.5

SLE25

F

29

19

positive

7

Ciclosporine, Pred

-

SLE26

M

21

79

positive

6

Pred, MMF

-

SLE27

F

37

118

positive

5

Pred, Aza

-

SLE28

F

74

20

negative

5

Antimalarials

-

SLE29

F

35

75

positive

6

Pred, Antimalarials

-

SLE30

F

33

35

positive

7

Pred, MMF

-

  1. Patient SLE18 was newly diagnosed and donated blood before immunosuppressive treatment was started. SLEDAI, systemic lupus erythematosus disease activity index; Pred, prednisolone; Aza, azathioprine; MTX, methotrexate; HCQ, hydroxychloroquine; MMF, mycophenolate mofetil; ND, not detected.