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Table 5 Association analysis of apo B with hyperuricaemia (left) and serum urate (right)

From: The relationship of apolipoprotein B and very low density lipoprotein triglyceride with hyperuricemia and gout

 

NU vs. HU and gout

 

Vs. urate in NU and HU groups

Unadjusted OR [95% CI]

P

Adjusted OR [95% CI]

P

Unadjusted β[95% CI]

P

Adjusted β[95% CI]

P

Total apo B ( μmol/L)

        

Europeans

0.58 [0.24-1.39]

0.22

0.46 [0.15-1.46]

0.19

-0.026 [-0.071-0.019]

0.26

-0.014 [-0.048-0.020]

0.41

Polynesians

0.27 [0.10-0.75]

0.012

0.20 [0.04-0.96]

0.044

-0.038 [-0.071--0.004]

0.031

-0.017 [-0.057-0.023]

0.40

Combined

0.41 [0.22-0.77]

0.005

0.47 [0.21-1.04]

0.062

-0.034 [-0.061--0.007]

0.013

-0.020 [-0.045-0.005]

0.12

VLDL apo B (0.1μmol/L)

        

Europeans

8.13 [2.04-32.42]

0.003

4.04 [0.82-19.83]

0.086

0.046 [0.011-0.081]

0.011

0.001 [-0.002-0.004]

0.48

Polynesians

2.32 [0.89-6.05]

0.084

1.81 [0.51-6.47]

0.36

0.045 [-0.007-0.098]

0.089

-0.002 [-0.004-0.0004]

0.099

Combined

3.80 [1.74-8.33]

0.001

2.50 [1.00-6.26]

0.050

0.046 [0.017-0.075]

0.002

-0.001 [-0.003-0.0005]

0.18

  1. Adjusted for age, BMI, type 2 diabetes, SSB intake (drinks/day), alcohol intake (drinks/week), eGFR, hypertension and prescription of lipid-lowering medication. The Polynesian data are also adjusted by number of self-reported Polynesian grandparents. The combined analysis was additionally adjusted by ancestral group. NU: normouricaemia; HU: hyperuricaemia; OR: odds ratio; CI: confidence interval; apo B: apolipoprotein B; VLDL: very low-density lipoprotein; BMI, body mass index; SSB: sugar-sweetened beverage; eGRF: estimated glomerular filtration rate.