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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Increasing expression of substance P and calcitonin gene-related peptide in synovial tissue and fluid contribute to the progress of arthritis in developmental dysplasia of the hip

Figure 1

Radiographs and experimental data of patients with developmental dysplasia of the hip. Radiographs depicting moderate developmental dysplasia of the hip (DDH) (A) and severe DDH (B). mRNA expression of substance P (SP) (C) and calcitonin gene-related peptide (CGRP) (D) in synovial tissues obtained from patients in the study groups: moderate DDH (n = 10), severe DDH (n = 11) and control (n = 8). *P < 0.05 versus control group. #P < 0.05 versus moderate DDH group. (E) through (I) Concentrations of neuropeptides (SP and CGRP) and inflammatory cytokines (interleukin (IL)-1β, tumor necrosis factor (TNF)-α and IL-10) were detected by enzyme-linked immunosorbent assay. *P < 0.05 versus moderate DDH. SF, Synovial fluid. Data represented are mean ± standard deviation.

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Arthritis Research & Therapy

ISSN: 1478-6362

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