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Table 2 Descriptions for synovial pathology scoring

From: Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis

Score

Description

0

No pathological changes

1

Minimal multifocal small (no measurable aggregates) subsynovial accumulations of inflammatory cells

2

Diffuse small (no measurable aggregates) subsynovial accumulations of inflammatory cells

3

Diffuse small subsynovial accumulations of inflammatory cells + 1–3 aggregates measuring at least 100 µM in diameter

4

Diffuse small subsynovial accumulations of inflammatory cells + >3 aggregates measuring at least 100 µM in diameter

5

Diffuse severe inflammation with numerous aggregates