Figure 5
From: Thyroid hormones enhance the biomechanical functionality of scaffold-free neocartilage
Collagen composition of Phase 1 and 2 constructs. Collagen content was normalized to tissue dry weight (COL/DW) and wet weight (COL/WW). PTH treatment in Phase 1 did not result in significant changes; however, T3 and T4 application during week 1 or 3 resulted in significant increases in collagen content. In Phase 2, T3 elicited the same effects. Sequential application of PTH did not alter the increases in collagen content induced by T3. Groups not connected by the same letter are statistically significant. Data are represented as mean ± standard deviation. PTH, parathyroid hormone; T3, tri-iodothyronine; T4, thyroxine.