Figure 1

Body weight. (A) Body weights (study week 4) in WT-chow (n = 15), WT-cholesterol (n = 14), ABIN1[D485N]-chow (n = 12) and ABIN1[D485N]-cholesterol (n = 14) fed mice. One-way ANOVA with post hoc Bonferroni correction. Grams (g) ± SE. B: Summary of baseline measurements (study week 0). Baseline (12 weeks of age) plasma cytokines for IL-1α, IL-10, and IL-6 in WT (n = 10) and ABIN1[D485N] (n = 9) mice (pg/ml ± SEM). Microvascular responses in WT and ABIN1[D485N] animals: endothelium-dependent responses (WT n = 14, ABIN1[D485N] n = 10), and maximal dilator capacity (WT n = 17, ABIN1[D485N] n = 15) (% change ± SEM).