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Table 8 A number of ingenuity pathway analysis canonical pathways were significantly affected in ageing tendon

From: Transcriptome analysis of ageing in uninjured human Achilles tendon

Name of canonical pathway

P value

Ratio

Hepatic fibrosis/Hepatic stellate cell activation

5.69 × 10−4

8/142 (0.056)

Oestrogen biosynthesis

1.61 × 10−3

4/38 (0.105)

Transcriptional regulatory network in embryonic stem cells

1.95 × 10−3

4/40 (0.1)

Glioblastoma signalling

3.66 × 10−3

7/159 (0.044)

Bupropion degradation

4.89 × 10−3

3/26 (0.115)

  1. The significance of the association between the data set and the canonical pathway was measured by using a ratio of the number of molecules from the data set that mapped to the pathway divided by the total number of molecules that map to the canonical pathway. Fisher’s exact test was used to calculate P values.