Expression of YAP transcript variants during micromass culture and chondrogenic differentiation of human synovial MSCs. (A) Expression of YAP transcript variants in human synovial membrane-derived (hSM)-MSCs immediately prior to (0 h) or 24 h after plating in micromass culture, shown as mean ± standard deviation (SD) (three donors) relative to pre-seeding (0 h) control. (B) Expression of YAP transcript variants in hSM-MSCs after 6 d of treatment with 10 ng/ml TGF-β1 or vehicle only in micromass culture, shown as mean ± SD (five donors) relative to vehicle-treated control. All data was normalised to GAPDH expression. *
P <0.05; **
P <0.01; ***
P <0.001. MSC, mesenchymal stromal/stem cell; TGF, transforming growth factor; YAP, Yes-associated protein.