Table 5 Frequency of human leukocyte antigen allele or haplotype in forms of sacroiliitis
From: Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype
Marker | Sacroiliitis | Symmetrical sacroiliitis | Asymmetrical sacroiliitis |
|---|---|---|---|
B*08:01 | 50.70% | 16.70% | 62.70% |
  P value | 0.006 | 0.066 | <0.000 |
 OR (95% CI) | 2.15 (1.06 to 1.77) | 0.323 (0.91 to 1.143) | 3.8 (1.9 to 7) |
B*27:05 | 23.20% | 61.10% | 9.80% |
  P value | 0.059 | <0.000 | 0.185 |
 OR (95% CI) | 1.92 (0.97 to 3.79) | 10.63 (3.86 to 29.3) | 0.52 (0.19 to 1.39) |
C*01:02 | 18.6% | 36.80% | 11.80% |
  P value | 0.027 | <0.000 | 0.9 |
 OR (95% CI) | 2.32 (1.08 to 5.00) | 5.57 (2.02 to 15.5) | 1.06 (0.41 to 2.76) |
C*02:02 | 10% | 26% | 4% |
  P value | 0.42 | 0.002 | 0.26 |
 OR (95% CI) | 1.47 (0.57 to 3.76) | 5.19 (1.67 to 16.1) | 0.43 (0.09 to 1.9) |
C*07:01 | 48.60% | 15.8% | 60.80% |
  P value | 0.119 | 0.022 | 0.001 |
 OR (95% CI) | 1.53 (0.89 to 2.62) | 0.25 (0.07 to 0.89) | 1.73 (1.47 to 5.1) |
B*08-C*07 | 47% | 16% | 59% |
  P value | 0.026 | 0.057 | <0.000 |
 OR (95% CI) | 1.86 (1.07 to 3.23) | 0.31 (0.089 to 1.1) | 3.18 (1.7 to 5.92) |
B*27-C*01 | 14.30% | 31.60% | 7.80% |
  P value | 0.064 | 0.001 | 0.78 |
 OR (95% CI) | 2.2 (0.94 to 5.15) | 5.9 (2.0 to 17) | 0.85 (0.28 to 2.61) |
B*27-C*02 | 8.6% | 26.3% | 2.00% |
  P value | 0.474 | <0.000 | 0.134 |
 OR (95% CI) | 1.44 (0.53 to 3.95) | 6.4 (2.0 to 20) | 2.4 (0.03 to 1.8) |