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Table 5 Frequency of human leukocyte antigen allele or haplotype in forms of sacroiliitis

From: Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype

Marker Sacroiliitis Symmetrical sacroiliitis Asymmetrical sacroiliitis
B*08:01 50.70% 16.70% 62.70%
P value 0.006 0.066 <0.000
 OR (95% CI) 2.15 (1.06 to 1.77) 0.323 (0.91 to 1.143) 3.8 (1.9 to 7)
B*27:05 23.20% 61.10% 9.80%
P value 0.059 <0.000 0.185
 OR (95% CI) 1.92 (0.97 to 3.79) 10.63 (3.86 to 29.3) 0.52 (0.19 to 1.39)
C*01:02 18.6% 36.80% 11.80%
P value 0.027 <0.000 0.9
 OR (95% CI) 2.32 (1.08 to 5.00) 5.57 (2.02 to 15.5) 1.06 (0.41 to 2.76)
C*02:02 10% 26% 4%
P value 0.42 0.002 0.26
 OR (95% CI) 1.47 (0.57 to 3.76) 5.19 (1.67 to 16.1) 0.43 (0.09 to 1.9)
C*07:01 48.60% 15.8% 60.80%
P value 0.119 0.022 0.001
 OR (95% CI) 1.53 (0.89 to 2.62) 0.25 (0.07 to 0.89) 1.73 (1.47 to 5.1)
B*08-C*07 47% 16% 59%
P value 0.026 0.057 <0.000
 OR (95% CI) 1.86 (1.07 to 3.23) 0.31 (0.089 to 1.1) 3.18 (1.7 to 5.92)
B*27-C*01 14.30% 31.60% 7.80%
P value 0.064 0.001 0.78
 OR (95% CI) 2.2 (0.94 to 5.15) 5.9 (2.0 to 17) 0.85 (0.28 to 2.61)
B*27-C*02 8.6% 26.3% 2.00%
P value 0.474 <0.000 0.134
 OR (95% CI) 1.44 (0.53 to 3.95) 6.4 (2.0 to 20) 2.4 (0.03 to 1.8)
  1. CI, confidence interval; OR, odds ratio.