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Table 7 Dactylitis is associated with both HLA-B*27:05 and B*08:01, but not HLA-C*06:02

From: Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype

HLA allele or haplotype

Frequency (%) of HLA

Odds ratio (95% CI)

P value (two-sided)

 

With trait

Without trait

  

B*27:05:02

21.3

9.8

2.5 (1.2 to 5.0)

0.009

B*27:05:02-C*01:02:01

12.0

5.3

2.5 (1.0 to 6.1)

0.05

B*27:05:02-C*02:02:02

8.7

4.5

2.0 (0.7 to 5.4)

0.2

B*08:01:01

42.7

30.3

1.7 (1.1 to 2.8)

0.03

B*08:01:01-C*07:01:01

42.0

29.3

1.8 (1.1 to 2.9)

0.03

C*06:02:01

25.3

33.8

0.7 (0.4 to 1.1)

0.1

B*44:02:01

9.3

22.0

0.37 (0.2 to 0.7)

0.003

B*44:02:01-C*05:01:01

8.7

18.0

0.43 (0.2 to 0.89)

0.02

B*44:03:01

6.0

15.2

0.36 (0.2 to 0.8)

0.012

B*44:03:01-C*16:01:01

3.3

9.8

0.3 (0.1 to 0.9)

0.03

  1. CI, confidence interval; HLA, human leukocyte antigen.