Fig. 2

CD105 and CD90 label endothelial cells in the DC tissue. DC samples were stained with antibodies recognizing CD90, CD105, vWF, SMA and desmin as indicated on the panels. CD105/CD90 double-positive cells localized in blood vessels in the DC tissue (a). CD105 is localized in vWF-expressing endothelial cells (b). No CD105-expressing cells can be identified in the SMA-positive myofibroblast layer encompassing CD105-positive endothelial cells (c). Desmin-positive pericytes surround vWF-expressing endothelial cells and no CD105/desmin double-positive cells can be identified (d). No CD90/SMA double-positive myofibroblasts could be identified (e). Desmin-positive pericytes surround CD90-expressing cells with a few desmin/CD90 double-positive cells (f, arrows). Ki67-expressing proliferative cells are concentrated in the vicinity of CD105-expressing activated endothelium (g). Scale bars: 20 μm. DC Dupuytren’s contracture, SMA smooth muscle actin, vWF von Willebrand’s factor