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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study

Fig. 2

Hemodynamic parameters, temperature, and symptoms. a Heart rate (HR). b Mean arterial pressure (MAP). c Temperature. d Score of self-reported symptoms. Data are expressed as mean and SEM of 10 subjects per group. The gray box indicates the period in which the (sham) stimulation took place. Within-group changes over time were all highly significant (p < 0.0001 for all parameters in both groups, calculated using repeated measures one-way ANOVA). p-values depicted indicate differences between groups over time calculated using repeated measures two-way ANOVA (interaction term). AU arbitrary units, LPS lipopolysaccharide, tVNS transvenous vagus nerve stimulation

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