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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Transvenous vagus nerve stimulation does not modulate the innate immune response during experimental human endotoxemia: a randomized controlled study

Fig. 3

Plasma concentrations of inflammatory cytokines. a Tumor necrosis factor (TNF)-α. b Interleukin (IL)-6. c IL-8 (d) IL-10. Data are expressed as medians of 10 subjects per group. Inserted bar graphs depict median and interquartile range of area under curve of cytokine time courses. Within-group changes over time were all highly significant (p < 0.0001 for all cytokines in both groups, calculated using Friedman tests). p-values depicted were calculated using Mann-Whitney U-tests. LPS lipopolysaccharide, tVNS transvenous vagus nerve stimulation

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