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Table 1 Baseline characteristics and demographics of patients included in the study

From: Comparison of two different folic acid doses with methotrexate – a randomized controlled trial (FOLVARI Study)

Mean ± SD (except where stated otherwise)

Folic acid 10 mg per week (FA10)

Folic acid 30 mg per week (FA30)

P value

N = 51

N = 49

Age, years

44.8 ± 10.0

43.8 ± 11.9

0.7

Female, number (%)

44 (86)

41 (84)

0.8

Duration of disease, years

4.4 ± 4.1

5.2 ± 5.1

0.4

Disease activity score (DAS28(3))

5.8 ± 0.9

5.7 ± 0.9

0.9

Tender joint count, 0–28

11.0 ± 4.8

11.2 ± 5.2

0.8

Swollen joint count, 0–28

5.1 ± 3.3

5.6 ± 3.6

0.5

HAQ, 0–3

1.1 ± 0.5

1.1 ± 0.5

0.7

Hemoglobin, g/dl

10.8 ± 1.7

10.9 ± 2.0

0.7

Serum albumin, g/dl

4.0 ± 0.5

3.9 ± 0.6

0.7

ESR, mm, first hour

65.4 ± 33.2

59.5 ± 30.0

0.3

Rheumatoid factor-positive, number (%)

42 (84)

35 (71)

0.2

ACPA-positive, number positive/number tested (%)

45/48 (94)

39/43 (91)

0.6

  1. DAS28(3) modified disease activity score using three variables, HAQ health assessment questionnaire (Indian), ACPA anti-citrullinated protein antibody