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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy

Fig. 4

Representative immunofluorescent images of torn human supraspinatus to show cell types expressing nociceptive neuromodulators. Panel shows dual antibody labelling for CD206 (green) with (a) glutamate (violet), (b) PGP9.5 (violet) and (c) NMDAR1 (red). Cyan represents POPO-1 nuclear counterstain. NMDAR1 co-localised with CD206-positive cells, whereas PGP9.5 and glutamate were predominantly expressed by resident tendon cells. Scale bar: 20 μm. mGluR metabotropic glutamate receptor, NMDAR N-methyl-D-aspartate receptor, PGP9.5 protein gene product 9.5

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