Fig. 1From: Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signaturesEsophageal intrinsic genes. A total of 2240 probes representing 2085 unique transcripts with the most similar expression between upper and lower biopsies for an individual but with the most dissimilar expression between individuals, termed ‘intrinsic’, were identified (false discovery rate (FDR) <1.1 %). An asterisk indicates samples obtained at 6 months. a Sample dendrogram, leaves are colored by group membership: red – samples from proliferative subset, purple – samples from inflammatory subset, black – samples from noninflammatory subset. Brackets indicate biopsies from the upper and lower esophagus for an individual that clustered together. b Overview of hierarchically clustered probes. c Selected gene clusters: purple, upregulated in inflammatory patients; red, upregulated in a proliferative subset of patients; black, downregulated in inflammatory patients. Additional file 9 contains the full list of transcriptsBack to article page