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Table 1 Clinical and laboratory data and arterial functional-structural properties in children with juvenile idiopathic arthritis and controls, adjusted by sex

From: Increased carotid artery intima-media thickness and myeloperoxidase level in children with newly diagnosed juvenile idiopathic arthritis

Parameters JIA group (n = 39) Control group (n = 27) p value
Age (yr) 13.0 ± 3.11 13.5 ± 3.08 0.5687
Body mass index (kg/m2) 21.2 ± 4.09 20.2 ± 4.04 0.3364
Peripheral systolic blood pressure (mmHg) 112.2 ± 8.7 108.9 ± 8.6 0.1375
Peripheral diastolic blood pressure (mmHg) 57.6 ± 5.01 57.1 ± 4.96 0.7360
Mean arterial blood pressure (mmHg) 74.0 ± 5.82 73.3 ± 5.77 0.6549
Central systolic blood pressure (mmHg) 92.0 ± 7.5 90.17 ± 7.4 0.3748
Central diastolic blood pressure (mmHg) 58.5 ± 5.07 58.4 ± 5.04 0.9249
Cholesterol (mmol/L)a 4.1 (3.8–4.3) 4.1 (3.8–4.4) 0.8150
LDL cholesterol (mmol/L)a 2.24 (2.06–2.43) 2.36 (2.13–2.60) 0.4324
HDL cholesterol (mmol/L) 1.50 ± 0.40 1.71 ± 0.40 0.0415
Triglycerides (mmol/L)a 0.87 (0.75–1.02) 0.70 (0.59–0.84) 0.0688
ADMA (μmol/L) 0.622 ± 0.175 0.679 ± 0.173 0.2040
MPO (ng/ml)a 115.2 (97.4–136.3) 57.6 (47.1–70.3) <0.0001
Adiponectin (ng/ml)a 8596.7 (7296.3–10,128.9) 9123.1 (7506.6–11,087.7) 0.6519
Mean IMT (mm) 0.46 ± 0.04 0.42 ± 0.04 0.0003
IMT SDS, height-specificb 1.694 ± 0.858 0.744 ± 0.852 0.0002
cfPWV (m/s)a 4.92 (4.71–5.14) 5.18 (4.90–5.47) 0.1579
AIx@75 (%) 0.642 ± 11.258 −2.042 ± 11.179 0.3811
  1. ADMA Asymmetric dimethylarginine, AIx@75 augmentation index values adjusted to a heart rate of 75 beats/min, cfPWV carotid-femoral pulse wave velocity, HDL high-density lipoprotein cholesterol, JIA juvenile idiopathic arthritis, LDL low-density lipoprotein cholesterol, MPO myeloperoxidase, SDS standard deviation score
  2. Values are mean ± standard deviation unless otherwise indicated
  3. aData were log-transformed before statistical analysis and are presented as geometric mean (95 % confidence interval)
  4. bData for34 patents with JIA and 23 control were analysed as reference values and are available for the height of 140 cm and taller [25]