Association between arthritis score at the onset of the disease and long-term locomotor outcome in adjuvant-induced arthritis in rats

Table 2 Effect of AIA on joint angles

		Control	AIA
		Control	More impaired hemibody	Less impaired hemibody
Joint angle during the stance phase (°)
Hip	Min	65.8 ± 9.1	50.4 ± 11.6^a	57.7 ± 11.9^b
Hip	Max	76.6 ± 9.1	62.3 ± 11.3^a	68.7 ± 11.4
Knee	Min	43.4 ± 9.5	42.1 ± 10.6	42.9 ± 11.0
Knee	Max	109.0 ± 14.1	89.8 ± 15.7^a	92.5 ± 16.0^a
Ankle	Min	75.9 ± 4.1	100.7 ± 12.5^a	98.1 ± 12.7^a
Ankle	Max	127.4 ± 8.7	129.0 ± 12.1	138.1 ± 11.5^a,b
ROM of ankle (°)		51.5 ± 8.0	28.3 ± 11.3^a	40.0 ± 16.3^b
Shoulder	Min	68.5 ± 6.7	78.7 ± 9.5^a	76.2 ± 8.5
Shoulder	Max	80.6 ± 8.9	93.8 ± 10.3^a	87.7 ± 9.2^a,b
Elbow	Min	54.2 ± 9.1	58.1 ± 7.4	52.7 ± 8.4 ^b
Elbow	Max	119.3 ± 9.7	115.7 ± 7.2	114.4 ± 10.7
Joint angles during the swing phase (°)
Hip	Min	62.3 ± 8.5	45.3 ± 12.0^a	53.6 ± 12.0^b
Hip	Max	70.6 ± 8.0	57.7 ± 10.5^a	64.0 ± 11.3^b
Knee	Min	41.0 ± 8.8	39.6 ± 8.9	39.8 ± 9.4
Knee	Max	109.0 ± 14.1	89.5 ± 16.0^a	92.3 ± 16.0^a
Ankle	Min	60.7 ± 6.2	96.7 ± 15.3^a	86.5 ± 15.2^a,b
Ankle	Max	112.7 ± 9.1	120.4 ± 12.3	125.7 ± 9.0^a
ROM of ankle (°)		52.0 ± 7.9	23.6 ± 9.5^a	39.2 ± 16.4^b
Shoulder	Min	67.9 ± 7.5	78.0 ± 10.1	74.6 ± 8.2
Shoulder	Max	81.2 ± 9.8	93.5 ± 10.7^a	86.6 ± 9.3^b
Elbow	Min	50.4 ± 8.2	53.7 ± 5.8	48.3 ± 6.8^b
Elbow	Max	118.0 ± 10.9	112.6 ± 8.6	114.0 ± 11.8

Parameters were measured in control (n = 8) and adjuvant-induced arthritis (AIA) rats (n = 18) at day 195 post-immunization. The more and less impaired hemibodies corresponded to hemibodies with the highest and lowest hind-paw diameter just before locomotion recording, respectively. Values are means ± SD. ^aSignificantly different from control rats (p <0.05). ^bSignificantly different from the more impaired hemibody (p <0.05). ROM range of motion

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