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Fig. 1 | Arthritis Research & Therapy

Fig. 1

From: IL-17 sequestration via salivary gland gene therapy in a mouse model of Sjogren’s syndrome suppresses disease-associated expression of the putative autoantigen Klk1b22

Fig. 1

Local IL-17 sequestration following IL-17R:Fc gene transfer to the salivary gland of Aec1/Aec2 mice. a Relative mRNA levels of the IL-17R:Fc fusion protein following gene transfer with varying amounts of an adenovirus vector (1E7, n = 4, 1E8, n = 5, 1E9, n = 5) or ultrasound-assisted gene transfer (UAGT)/IL-17R:Fc (n = 4). Error bars are + standard error of the mean. b Western blot analysis of salivary gland tissue treated with UAGT/IL-17R:Fc relative to UAGT/Luciferase (Luc) and the background strain. Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) was used as a housekeeping control

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Arthritis Research & Therapy

ISSN: 1478-6362

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