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Table 3 Path analysis for direct analgesic effect on the reduction of the BPI average pain score

From: A randomized, double-blind, placebo-controlled phase III trial of duloxetine in Japanese fibromyalgia patients

Week Direct effect Indirect effect
Week 2a 84.3 15.7
Week 4a 83.8 16.2
Week 6a 63.1 36.9
Week 10a 43.2 56.8
Week 14a 41.6 58.4
Endpointb 28.3 71.7
  1. Values are the percentages of direct and indirect effects
  2. aObserved case
  3. bLast observation carried forward